Causes

The virus of dengue fever belongs to the family flaviviridae. It is the RNA virus. Other member of the Flaviridae virus is the virus of yellow fever, virus of West Nile, virus of encephalitis of St. Louis, virus of Japanese encephalitis, virus of encephalitis of...

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Effects

The children who are below the age of 10 years get affected on the functioning of circulatory system during the dengue fever. The mortality rate lies in between the 6 to 30% and it is found that most of the death occurred in the patients of dengue...

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Treatment

It is found that at present there is no specific vaccine is found which can kill the virus of dengue fever not even a single anti virus tablets.
Dengue fever is treated by a medicine which is known as Paracetamol, an anti pyretics...

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Analysis of Dengue

Now-a-days, the treatment of dengue fever is become clinically. The treatment becomes easier by determining the symptoms and through examination of body physically. This mostly applies in the area which is endemic. In earlier times, it became difficult for doctors to differentiate between dengue fever and of any viral infection. Now doctors start diagnosing the disease through the fever which is accompanied by vomiting, rashes, nausea, headache, pain in the body, blood cell become low in count etc. If anyone is found with these symptoms in the endemic area, they are sent for proper treatment as soon as possible. These are the warning signs mainly occurring before the onset of dengue fever.

The treatment should be suggested to those who are the victims of fever for more than two weeks. It become difficult for the doctors to distinguish between dengue fever and chikangunaya fever as there is similar type of viral infection sharing the most of the symptoms of dengue and occurs mostly in the dengue prone areas. There is an investigation held in order to exclude the factors which can cause symptoms similar to dengue. They are Malaria, viral fever of hemorrhagic, measles, leptospirosis, influenza, fever of typhoid and the last but not least disease of meningococcal.

The changes which are earlier detectable in the investigation of laboratory is that the platelets of white blood cells start declining, which is accompanied by acidosis of metabolism and also accompanied by low platelets.

In many of the diseases, it found that there is a leakage from plasma which results in the situation of hypoalbuminemia and the situation of hemoconcentration. During the physical examination, there is detection of ascites when it is large but there will be the demonstration of ultrasound and also the demonstration of fluid at stage which is the starting of DSS.

Classification

Dengue fever has been divided into groups by the classification report given by World Health Organization (WHO) in the year 2009. It is divided into two groups: first is uncomplicated and second is severe. Severe stage of dengue is the situation where there is leakage of severe plasma, severe bleeding and dysfunction of severe organs while the remaining cases are uncomplicated. According to the report of WHO 1997, it is said that dengue has been divided into various fever which are not differentiable. They are dengue fever and hemorrhagic dengue fever. There is also the subdivision of fever named by dengue hemorrhagic into the grades from I-IV. Grade I of hemorrhagic fever is use in the case of easy bruising and also test of positive tourniquet in any one who is suffered with fever, grade II is the grade which is present just because of the bleeding in spontaneous in the part of skins and somewhere else in the body, grade III is act as the evidence for shock and last grade IV is act in the case of blood pressure and in the case where the pulse of the body cannot be detect.

Laboratory Tests

Micro biological testing of laboratory helps in the diagnosis of dengue fever. The diagnosis can be done with the help of isolation of viruses in the cell cultures, detection of viral antigen and in the detection of specific antibodies, detection of nucleic acid through PCR. It is found that the detection of nucleic acid and the detection of viral isolation acts to be more correct than the detection of antigens. But these are the tests which are not easily available because of their high cost.

The result of the entire test was found negative in the starting stage of dengue disease. PCR and the antigen, which is viral, play a vital role in the starting seven days of the fever. In the year 2012, there was the introduction of the PCR test which is run on medical equipments used in the process of diagnosing Influenza.

It is found that the test for dengue virus is only useful in the diagnosing of dengue in the stage which took sometime after infection. The duration of the lgM and lgG to get produced is from 5-7 days. The maximum level of lgM is get detected by following the infection which is in primary stage but the other test of dengue which is known by the name lgG is produced in the following other stages such as in secondary stage or in tertiary stage. The lgM is the test which cannot be determined after few days from primary infection but through re-infection processes, it becomes easy to detect the lgG over 60 years. Once the patient is infected with primary infection lgG of the test starts reaching to a level after duration of 14-21 days in the blood.

Both types of test lgM and lgG provide immune capacity to different types of serotypes.